Like snowflakes, each EV is unique.

Direct Biologics is developing investigational, secretome-based product candidates derived from adult bone marrow mesenchymal stem cells for evaluation in clinical research. These candidate therapies are investigational and have not been approved by the U.S. Food and Drug Administration.

Our cGMP manufacturing processes are designed to support consistency, scalability, and quality from sourcing through characterization—providing a foundation for advancing clinical research programs.

Cells naturally release a variety of materials into their surrounding environment. Some of these, known as extracellular vesicles (EVs), are small particles that have become an area of increasing scientific interest.

EVs are one part of a broader group of materials referred to as the secretome, which also includes proteins, lipids, and other biomolecules.

The secretome is being studied in research settings to better understand their characteristics and potential roles in biological systems.